中文版
Pain Translational Research Group

The analgesic mechanism of transcutaneous electrical nerve stimulation - evidence from EEG

Pain is a major obstacle to patient rehabilitation, especially in chronic pain, which places a heavy burden on patients and medical institutions. Therefore, the development of an effective analgesic strategy is extremely important. Based on this, we used the SXC-4A type electric stimulator developed by the laboratory, to explore the analgesic mechanism of transcutaneous electrical nerve stimulation (TENS) from the perspective of EEG. Experimental results show that low-frequency (2Hz) TENS in stimulating the ipsilateral and contralateral have a good analgesic effect, and high-frequency (100Hz) TENS analgesic effect only appears to stimulate the ipsilateral. This result suggests that high frequency TENS and low frequency TNES may involve different analgesic mechanisms, that is, high frequency TENS analgesia may be a local spinal analgesia, and low frequency TENS may involve advanced central involvement.

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